Open connected medicine is a group of related projects aimed at enabling medical professionals to take full advantage of the connectivity capabilities of medical devices to enhance the quality of care for their patients. Our approach is to build a community focused on developing and enabling widespread adoption of open hardware and software for various clinical needs where connectivity can enhance care, and sharing of best practices and lessons learned in putting this technologies to use in patient care.
The three current major projects under the open connected medicine initiative are briefly described below. We also work on miscellaneous projects related to connectivity, integration, and technology to support patient care. Contact us if you would like to support or collaborate on our work of if you have a project in mind you think is of mutual interest.
The open medical application platform (openmedap) a platform for experimenting with connectivity of medical devices to form a medical application platform, as well as experimenting with applications that leverage the connectivity of devices to support patient care.
We are working on a release of this software that is more accessible to others. Contact us if you would like to work with the current version of the software. You can see a demonstration of openmedap’s capabilities for closed-loop physiology management applications here: https://openmedap.openconnectedmed.org/demo
The closed-loop assistant simulation framework (CLAsim) is a framework for experimenting with the kinds of applications openmedap enables using virtual patients. It is focused more on closed-loop physiology management, but can be leveraged for other applications. It provides both software-only simulation to rapidly prototype ideas as well as system-in-loop simulation where virtual patients can interact with a full openmedap hardware-software system in real-time to experiment with realistic scenarios.
You can find out more about CLAsim on its project page.
The open medical laboratory connectivity platform is a project focused on providing means for laboratory technicians to capture lab test results from various pieces of equipment and push the data captured directly to the electronic health record. This eliminates the need for manual input and reduces the errors associated with manual data entry.
We are in the early stages of this project and will have more to report soon.
Collaborators and Contributors
The following people at the listed institutions work together on various aspects of the open connected medicine initiative:
A team of students led by Philip Asare, Assistant Professor in Electrical and Computer Engineering, has been working on the open connected medicine initiative since 2015 in collaboration with the other institutions listed below. The Bucknell team is the core development team for the open connected medicine initiative projects. The following students (alphabetical order) at Bucknell have contributed to this project at one point or another:
- Aditya Acharya, Mechanical Engineering ’19
(now MS student in Aerospace Engineering, Virginia Tech)
- Laurène Belliard, (visiting summer intern) Ingénierie Electronique et Electrique ’19, Polytech Tour
- Sam Citron, Computer Science and Engineering ’22
- Mateo Conde, Computer Engineering ’21
- Farooq Gessa, MS in Electrical Engineering ’19
- Yuxuan Huang, Computer Engineering ’17
(now MS student in Computer Software Engineering, Western University)
- Dikendra Karki, Electrical Engineering ’19
- Win Kyaw, Electrical Engineering ’19
(now Associate Engineer, PTTEP)
- Chen (Raphael) Liu, Electrical Engineering ’18
(now MS student in Electrical Engineering, Columbia University)
- Caitlin Mahoney, Markets, Innovation, and Design ’19
- Yash Mittal, Computer Science and Engineering ’19
(now Software Engineer, Pinterest)
- Mateen Qureshi, Computer Engineering ’19
(now Technology Analyst, Deloitte Consulting)
- Ava Warfel, Biology ’22
- Devin Whalen, Computer Engineering ’22
- Yunyingying (Sarah) Xu, Computer Engineering ’18
(now Software Engineer 2, PayPal)
Department of Perioperative Medicine, National Institutes of Health Clinical Center
Taimoore (Tim) Rajah, previously with the department, provided early input and motivation for the project. Tim was instrumental in setting up the collaboration with CME America as well as the team at Brown University. Andrew Mannes, Chief of the department, also provided early clinical perspective and motivation for the project.
The open connected medicine initiative started as a partnership between Philip Asare’s team at Bucknell and Mark Poler, Vice Chairman in the Anesthesiology Department at Geisinger and Past President of the Society for Technology in Anesthesia, through funding from the Bucknell-Geisinger Research Initiative. John McIlwane, Program Director of the eICU Program and Medical Director for the Center for Telehealth, has also been an active clinical partner. Geisinger provides clinical expertise as well as access to medical equipment for our experiments. They have hosted the Bucknell team at the Geisinger Medical Center in Danville, PA multiple times to enable the team understand the clinical needs by observing clinicians in action and interacting with professionals involved in supporting patient care.
C. Nataraj, Director of the Villanova Center for Analytics of Dynamic Systems (VCADS) and Qianhong Wu, Associate Professor in Mechanical Engineering, have been providing their modeling and algorithm development expertise. Their modeling work is instrumental to continued development of clasim, and their algorithm development work contributes to developing closed-loop applications to showcase the capabilities of openmedap.
CME America has been gracious enough to loan us pumps and allow us to interact with their engineers. This is has been very important to developing our closed-loop demos, which allows us to set up a good testbed for both openmedap and CLAsim.
Adewole Oyalowo and Uday Agrawal worked on an open source project called pyMIND in the Laboratory for Cognitive Neurophysiology & Neuromodulation led by Wael Asaad at Brown University where they developed code to interface with the Philips MPXX series monitors. This code, which they were happy to share with us, in what we believe to be the open connected medicine spirit we are trying to cultivate, is critical to the device driver we have developed for Philips MPXX series monitors.
Rachel Clipp and Aaron Bray in the Medical Computing Team at Kitware, Inc. have been valuable partners in the development of CLAsim, which relies on the Pulse physiology engine that they developed and continue to work on.
eHealthAfrica is a new partner interested in connecting the medical devices in their newly-opened clinic in Nigeria. We are working with them on device drivers for their devices, focusing currently on lab equipment. Our long-term goal there is to also put openmedap or similar connectivity solution into action in their clinic environment.